Mice seriously help science uncover new ways to cure old diseases and problems that bugged people for centuries. In todays Mice in Science- Gene Therapy successfully helped restore hearing in deaf mice.
Jeffrey Holt of Boston Children’s Hospital and Harvard Medical School said that their gene therapy procedure wasn’t ready yet for clinical trials as they needed to modify it a bit but in the not so far future we might start seeing human trials.
The tests had been done on two muted mice, with the first the TMC1 gene was completely removed which is a good way to stimulate recessive TMC1 mutations in humans: Children with two mutant copies of TMC1 have profound hearing loss from a very young age.
With the first mutate mice the gene therapy with TMC1 regenerated the ability of sensory hair cells to respond to sound producing along with restored activity in the auditory portion of the brainste, with the second test which the mice had dominant deafness model, the testing with TMC2 showed better results in which it’s completely restore the lost hearing.
According to Holt all it would take is an injection into their ears to restore hearing.
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